Have you ever calculated how many molecules of a drug you swallow with a single pill? Let's assume you swallow one pill of a common painkiller. At a dosage of 500 mg, this corresponds to approximately 1,991,929,081,767,663,403,016 molecules per pill.
In other words, you have pain, which is typically very localized. By taking the painkiller, the body is flooded with billions and billions of molecules, which leads to success - the pain goes away. But does the flood of drug molecules have unwanted side effects?
Wouldn't it be much more efficient if just a few drug molecules were administered specifically where the pain actually occurs? This is the exciting task of nanomedicine.
InnoMedica packages medicines in capsules that are more than 20,000 times smaller than a human hair. These are unimaginably small sizes that can only be seen with special microscopes. These nanocapsules are called liposomes. genannt.
If a drug is packaged in a liposome, it acts and behaves differently to a free soluble substance (actually dissolved in body water). In the nanoparticle, it is transported together with all other packaged drug molecules to the right place in the body at the same time with increased accuracy and the individual molecules do not all have to find a target for themselves. Compared to freely soluble drugs, liposomal drugs therefore allow more efficient drug delivery to the target site in the body. This efficiency ultimately benefits the patient and opens up previously unthinkable possibilities in pharmaceutical medicine.
Liposomes are the ideal size for attaching to cells and releasing a drug into the cells. As a result, the drug remains protected on its way to the target cell, is not lost and does not cause any damage to other parts of the body.
There are many diseases that would benefit from drug delivery in liposomes. For example, it is difficult to transport a drug into the brain. With a brain-permeable liposome, however, the concentration of a drug in the target tissue can be increased, which enables efficient long-term therapies for Parkinson's patients, for example.
Nanomedicine therefore makes it possible to release drugs in the human body in a targeted manner and thus increase the efficiency of the drug.