{"id":776,"date":"2024-03-19T19:44:56","date_gmt":"2024-03-19T18:44:56","guid":{"rendered":"https:\/\/innomedica.dev.hayloft-it.ch\/?page_id=776"},"modified":"2026-02-10T16:38:20","modified_gmt":"2026-02-10T15:38:20","slug":"our-nanocarriers","status":"publish","type":"page","link":"https:\/\/innomedica.com\/en\/technologie\/unsere-nanocarrier\/","title":{"rendered":"Our Nanocarriers"},"content":{"rendered":"<div class=\"wp-block-cover alignfull is-light has-custom-content-position is-position-bottom-left is-style-has-overlay\"><img loading=\"lazy\" decoding=\"async\" width=\"8192\" height=\"5464\" class=\"wp-block-cover__image-background wp-image-814\" alt=\"\" src=\"https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-02-Innomedica_Marly_047.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-02-Innomedica_Marly_047.jpg 8192w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-02-Innomedica_Marly_047-300x200.webp 300w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-02-Innomedica_Marly_047-1024x683.webp 1024w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-02-Innomedica_Marly_047-768x512.webp 768w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-02-Innomedica_Marly_047-1536x1025.webp 1536w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-02-Innomedica_Marly_047-18x12.webp 18w\" sizes=\"auto, (max-width: 8192px) 100vw, 8192px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-0 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<h1 class=\"wp-block-heading has-text-align-left has-huge-font-size\">Our Nanocarriers<\/h1>\n\n\n\n<p class=\"has-light-color has-text-color has-link-color has-small-font-size wp-elements-ec4cd441417ee35f96ca524ec0b1a9dd\"><\/p>\n<\/div><\/div>\n\n\n<nav aria-label=\"breadcrumb\"><ol class=\"breadcrumb\"><li class=\"breadcrumb-item\"><a href=\"https:\/\/innomedica.com\/en\">Home<\/a><\/li>\n<li class=\"breadcrumb-item active\" aria-current=\"page\">Our Nanocarriers<\/li><\/ol><\/nav>\n\n\n<div class=\"wp-block-group alignwide is-style-default is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"is-style-lead has-small-font-size\"><strong>Nanocarriers are highly specific delivery systems designed to transport therapeutic agents directly to their site of action and release them in a controlled manner. InnoMedica utilizes liposomal nanocarriers that are modeled on the body\u2019s natural transport mechanisms.<\/strong><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-media-text alignwide has-media-on-the-right is-stacked-on-mobile is-vertically-aligned-top\" style=\"grid-template-columns:auto 45%\"><div class=\"wp-block-media-text__content\">\n<p>Liposomal nanocarriers consist of a lipid bilayer structure. They are loaded with a therapeutic agent to enable its targeted delivery to the site of disease, thereby minimizing exposure of healthy tissue. Prolonged circulation time in the bloodstream combined with controlled release at the site of action is intended to enhance efficacy while reducing side effects. Owing to their modular structure, these nanocarriers can be combined with a wide range of active substances.<\/p>\n\n\n\n<p>The current focus of application lies in neurology, where InnoMedica is developing a therapy for Parkinson\u2019s disease aimed at addressing the neurodegenerative processes underlying the condition.<\/p>\n<\/div><figure class=\"wp-block-media-text__media\" data-no-zoom=\"true\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-01-Innomedica_Laser_Vials_08-1-1024x683.webp\" alt=\"\" class=\"wp-image-692 size-full\" srcset=\"https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-01-Innomedica_Laser_Vials_08-1-1024x683.webp 1024w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-01-Innomedica_Laser_Vials_08-1-300x200.webp 300w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-01-Innomedica_Laser_Vials_08-1-768x512.webp 768w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-01-Innomedica_Laser_Vials_08-1-1536x1024.webp 1536w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-01-Innomedica_Laser_Vials_08-1-2048x1366.webp 2048w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/03\/24-01-Innomedica_Laser_Vials_08-1-18x12.webp 18w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">TLN-1 a liposomal nanocarrier formulation incorporating GM1, with potential applications in a range of neurological disorders<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Current development focus: Parkinson\u2019s disease<\/h2>\n\n\n\n<p>The nanocarrier developed for InnoMedica\u2019s neurology program is designed to transport the membrane-integrated active substance GM1 ganglioside across the blood\u2013brain barrier. GM1 ganglioside is an essential component of neuronal cell membranes and plays a central role in neuronal development, signal transmission and storage, regenerative processes, and the release of neurotrophic factors \u2014 signaling molecules that are critical for the survival and regeneration of nerve cells. By means of the nanocarrier technology, increased levels of GM1 can reach the site of action in the brain, enabling its neuroprotective and neuroregenerative effects. As an endogenous substance, GM1 is generally well tolerated.<\/p>\n\n\n\n<figure data-no-zoom=\"true\" class=\"wp-block-image aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TLGM-whole-structure-1024x576.webp\" alt=\"\" class=\"wp-image-1458\" style=\"width:654px;height:auto\" srcset=\"https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TLGM-whole-structure-1024x576.webp 1024w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TLGM-whole-structure-300x169.webp 300w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TLGM-whole-structure-768x432.webp 768w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TLGM-whole-structure-1536x864.webp 1536w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TLGM-whole-structure-2048x1152.webp 2048w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TLGM-whole-structure-18x10.webp 18w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">TLD-1 a liposomal nanocarrier formulation incorporating doxorubicin, with potential use in a broad range of cancer indications.<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Current development focus: soft tissue sarcoma (STS)<\/h2>\n\n\n\n<p>The nanocarrier used in InnoMedica\u2019s oncology product delivers the established active substance doxorubicin and is designed to mitigate its known severe side effects. An optimized surface coating of the nanocarrier reduces interaction with healthy tissue. The extended circulation time supports controlled drug exposure and may help reduce the burden on elimination organs. Its particularly small particle size facilitates targeted penetration into tumor tissue and promotes higher local drug concentrations within the tumor.<\/p>\n\n\n\n<figure data-no-zoom=\"true\" class=\"wp-block-image aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TALIDOX-whole-structure-1024x576.webp\" alt=\"\" class=\"wp-image-1457\" style=\"width:654px;height:auto\" srcset=\"https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TALIDOX-whole-structure-1024x576.webp 1024w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TALIDOX-whole-structure-300x169.webp 300w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TALIDOX-whole-structure-768x432.webp 768w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TALIDOX-whole-structure-1536x864.webp 1536w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TALIDOX-whole-structure-2048x1152.webp 2048w, https:\/\/innomedica.com\/wp-content\/uploads\/2024\/04\/TALIDOX-whole-structure-18x10.webp 18w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p>InnoMedica\u2019s nanocarrier platform provides the technological foundation for targeted therapeutic strategies \u2014 from Parkinson\u2019s disease to oncology and beyond.<\/p>\n\n\n\n<p class=\"has-text-align-center\"><\/p>\n\n\n\n<p class=\"has-text-align-center\"><\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Nanocarrier sind hochspezifische Transportsysteme, die therapeutische Wirkstoffe gezielt an den Wirkort bringen und dort freisetzen. InnoMedica verwendet liposomale Nanocarrier, die den nat\u00fcrlichen Transportmechanismen des K\u00f6rpers nachempfunden sind. Liposomale Nanocarrier bestehen aus einer Lipid-Doppelschicht. Sie werden mit einem Wirkstoff beladen, um ihn gezielt zum Krankheitsherd zu bringen, wodurch gesundes Gewebe geschont werden soll. Die l\u00e4ngere Verweildauer [&hellip;]<\/p>\n","protected":false},"author":12,"featured_media":0,"parent":63,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-776","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/pages\/776","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/comments?post=776"}],"version-history":[{"count":27,"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/pages\/776\/revisions"}],"predecessor-version":[{"id":2818,"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/pages\/776\/revisions\/2818"}],"up":[{"embeddable":true,"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/pages\/63"}],"wp:attachment":[{"href":"https:\/\/innomedica.com\/en\/wp-json\/wp\/v2\/media?parent=776"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}