Targeted Disease Treatments: InnoMedica’s Nanotechnology Can Make It Happen.
InnoMedica has already developed a diversified product pipeline based on its liposomal technology platform. All pipeline products build and improve on established active substances with known efficacy profiles, rather than requiring new molecules. Such an approach is interesting from both a medical point of view, as well as regarding entrepreneurial risks and returns. Therapeutic effects of known substances are improved substantially by combining them with the biologically fine-tuned nanocarrier. This approach promises the development of medicines with high chances of translational success, as well as large therapeutic advantages for patients.

Talidox®
This highly effective chemotherapy can convince even in late-stage cancers. Talidox substantially improves the benefit/side-effect profile without causing any serious side-effects. With the safety study already completed, InnoMedica has submitted its application for market approval to Swissmedic in fall 2021.

Talineuren®
Fostering regeneration instead of merely preventing degeneration – InnoMedica’s novel and innovative therapeutic approach introduces a paradigm shift to neurology. It promises to revolutionize the therapeutic prognosis for patients with Parkinson’s Disease or Amyotrophic Lateral Sclerosis (ALS). This spring 2021, Talineuren has received an orphan drug designation by the FDA and the EMA for application in ALS.

Product Pipeline
In addition to Talidox (oncology), Talineuren (neurology), and TaliCoVax19 (infectiology), InnoMedica is currently developing a second drug treatment against cancer, a medicine against arteriosclerosis, as well as a contrast agent for marking tumors for more precise surgical removal. Furthermore, InnoMedica is researching a medical solution for combatting resistant bacterial strains in a cooperation project with the University of Bern.

Licensing
InnoMedica’s nano transport system is already in use in first products in oncology, neurology, and infectiology. This technology platform enables the optimization of various types of medicinal agents by improving their efficacy while reducing side effects. InnoMedica is actively examining cooperation with academic and industrial partners.
Pharmaceuticals efficiently targeted
InnoMedica’s nano transport system directly delivers pharmaceutical agents at the source of a disease by encapsulating them in a nanocarrier. InnoMedica’s Talidox delivers an established anti-cancer drug directly in the tumor. The liposomal design of Talineuren even enables bridging the blood-brain barrier for the delivery of a regenerative agent in neurological treatments.
Statements
Statements on Our Work
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PD Dr. Michael Schüpbach
Vice President, Swiss Movement Disorder Society“Treatment with GM1 has already shown positive results in initial studies in patients with Parkinson's disease. Talineuren®, the liposomal formulation of GM1, is a promising substance whose therapeutic potential we now want to test in a clinical trial. Orphan drug status would also be a significant step for Talineuren® towards rapid market approval.”
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Prof. Dr. Beat Thürlimann
St. Gallen Breast Cancer Center“The successfully completed Phase I study lays the foundation for the further development of Talidox®, which will take place internationally at renowned breast cancer centers. We expect this to lead to successful further development of the drug in breast cancer. The currently favored first line therapy for breast cancer is weekly infusions of paclitaxel (e.g. Taxol). Talidox® has the potential to become the new standard in breast cancer chemotherapies.»
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“The main requirement for obtaining a market approval for a formulation such as Talidox®, is a safety study in humans.”
Prof. Dr. Matthias G. Wacker
Department of Pharmacy, Faculty of Science, National University of Singapore. Consultant for US Pharmacopeia (USP) and National Formulary (NF) -
Swissmedic categorizes Talidox as known substance with innovation
“Thus, the efficacy is basically considered to be given and the manufacturer only has to show to what extent the changes in the drug affect the therapeutic performance.”
Swissmedic categorizes Talidox as known substance with innovation